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The Fight Against Osteosarcoma Is Personal

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A Laser Focus on Osteosarcoma Survival

The OSI is the only national organization focused exclusively on finding better treatments, and ultimately, a cure for osteosarcoma — the most common pediatric bone cancer. There have been no new treatments approved for osteosarcoma in 40 years, and patients deserve better. Join us in concentrating on the cure.

James Morrow, MD, PhD

For Researchers

We fund the most promising and breakthrough clinical trials and science to identify new treatment options for osteosarcoma patients for whom first-line therapy has failed. Learn how you can apply for funding.

Faith playing outside with her arms and legs stretched out

For Patients

We offer free expert advice for patients and families affected by osteosarcoma, and we can help connect you to relevant clinical trials. Find answers to your urgent questions about osteosarcoma. Se habla español.

For Supporters

We work to raise awareness and galvanize advocacy of osteosarcoma by sharing stories of progress, inspiration, and information in overcoming osteosarcoma. Read the latest patient stories and research updates.

Osteosarcoma Statistics

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Osteosarcoma is the most common childhood bone cancer.

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No new treatments have been approved for osteosarcoma patients in 40 years.

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1 in 3 children with osteosarcoma will not survive.

The OSI Brings Together the Brightest Minds in Osteosarcoma

Stories of Inspiration & Community

Teenage Jayden and his mom, Ashley Selby-Karney, standing and smiling into the camera. Jayden's shirt reads, "Covenant Kids."
Finding Purpose After a Series of Osteosarcoma Relapses

Despite amputation and multiple relapses, 14-year-old Jayden has not lost his eagerness to encourage others — and neither has his mom, Ashley.

Osteosarcoma Survivor Chooses Amputation Over Chronic Pain

After six years of debilitating pain following a limb salvage surgery, Sloane Dyer, 18, decided to let go of their leg in order to move on with their life.

One Patient’s Advice for Brightening the Hard Days

Osteosarcoma survivor Annabelle Grace, who goes by AG, shares her best advice for coping with grueling cancer treatment.

What We Do

Our Strategy

Globally estimated, there are over 26,000 new cases of osteosarcoma diagnosed each year, with 1,000 being diagnosed in the United States, but treatment options haven’t advanced in 40 years. To find a cure for osteosarcoma, we have to collaborate, innovate, and translate around the most promising science.

Our Mission

The mission of the Osteosarcoma Institute is to dramatically increase treatment options and survival rates in osteosarcoma patients through identifying and funding the most promising and breakthrough osteosarcoma clinical trials and science.

Our Impact

Funding, removing obstacles, raising awareness & working together. The Osteosarcoma Institute funds breakthrough clinical trials and science to identify new treatments, and ultimately a cure for osteosarcoma. 

$5,500,525

to Translational Studies

$1,480,000

to Clinical Trials

$1,120,000

to Correlative Science

$521,329

to Discretionary Grants

Concentrate on the Cure with Us

The Osteosarcoma Institute’s mission is to dramatically increase treatment options and survival rates in osteosarcoma patients through identifying and funding the most promising and breakthrough osteosarcoma clinical trials and science.