Join Us in Concentrating on the Cure for Osteosarcoma

Institutional Collaborators

To OSI, No New Options is Not an Option

There have been no new treatment options approved for osteosarcoma in nearly 40 years. This is not acceptable to the Osteosarcoma Institute. Our healthcare visionaries, founders, staff, and board members have all been impacted by osteosarcoma in their personal lives and careers. We are taking on the persistent problem of osteosarcoma with urgency and a new approach because we care deeply about this mission.

It’s not because it’s the right thing to do, it’s because it’s unacceptable not to do it. 
-Mac Tichenor, OSI President

The mission of the Osteosarcoma Institute is to dramatically increase treatment options and survival rates in osteosarcoma patients through identifying and funding the most promising and breakthrough osteosarcoma clinical trials and science. The Osteosarcoma Institute funds breakthrough clinical trials and science to identify new treatments, and ultimately a cure for osteosarcoma.

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Our Impact

Funding, removing obstacles, raising awareness & working together. The Osteosarcoma Institute funds breakthrough clinical trials and science to identify new treatments, and ultimately a cure for osteosarcoma.


to Translational Studies


to Clinical Trials


to Correlative Science


to Discretionary Grants


Find information on our funded work, grants to translate scientific discoveries into new therapies, and osteosarcoma science to identify new treatment options for osteosarcoma patients for whom first-line therapy has failed.


Osteosarcoma patients should not have to face the reality that no new treatments have been approved for osteosarcoma in 40 years. Find information on how we are supporting patients through OSI Connect and pursuing the latest developments in improving the outcomes for patients.

Our Story

The OSI was initially conceived at an osteosarcoma expert panel conference held in Jackson Hole, Wyoming in the summer of 2015. Over the course of the conference, the evidence showed that there had been no progress in osteosarcoma treatments over the past ten years (in fact, over the past 35 years). A stark consensus emerged that the existing, traditional paradigm for seeking advancements had failed and a new paradigm was needed.

OSI Connect

Osteosarcoma Answers and Assistance

OSI Connect is our free, easy-to-use resource for patients who have been diagnosed with osteosarcoma, or suffered a relapse after inital treatment. These events are devastating and overwhelming, and start a desperate pursuit to gain knowledge and understanding. Often people turn first to the internet but encounter an avalanche of search results with no way to assess their accuracy, quality, or applicability. This resource helps patients and their families find answers to their questions from an experienced, knowledgeable osteosarcoma physican about all aspects of the disease, including treatment, possible side effects, and advice for getting the most out of your visits with your treating physician. Se habla español.

Colette R.

Mother of Osteosarcoma Patient

“As a mother with a 13-year-old osteowarrior, I couldn’t rest without knowing I am doing absolutely everything to give her the best care. OSI Connect gave me that peace of mind and the reassurance that I’m doing everything possible for my daughter. They are knowledgeable, kind and compassionate.”

Lei Z.

Mother of Osteosarcoma Patient

“I encourage other parents to seek out as much information as possible. Organizations like the OSI and other local support groups have been hugely helpful along the way.”


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