Concentrating On The Cure
The OSI Hotline is the only hotline dedicated to supporting those impacted by osteosarcoma. This free resource connects patients, families, and caregivers with knowledgeable osteosarcoma expert physicians to answer questions about all aspects of the disease. The OSI Hotline physicians can discuss available treatments, possible side effects, and provide helpful advice for getting the most out of your visits with your treating physician.
Hotline Frequently Asked Questions
What is the Osteosarcoma Information Hotline? How can it help?
This free Hotline is for patients who have been diagnosed with osteosarcoma, or suffered a relapse after initial treatment. These events are devastating and overwhelming, and start a desperate pursuit to gain knowledge and understanding. Often people turn first to the internet but encounter an avalanche of search results with no way to assess their accuracy, quality, or applicability. This resource will help patients, families, and caregivers find answers to their questions from experienced, knowledgeable osteosarcoma expert physicians about all aspects of the disease, including available treatments and possible side effects, as well as helpful advice for getting the most out of your visits with your treating physician.
How does it work?
A member of the Osteosarcoma Institute staff will answer your call or email and, on a confidential basis, gather your information and questions for review by one of the sarcoma experts who serves on our board. After this review, we will arrange a phone call between you and the expert.
The Osteosarcoma Information Hotline provides general guidance about the treatment of osteosarcoma. This Hotline resource will help patients, their families and physicians. We can provide referrals for care if you wish. We do not provide medical care or specific medical advice.
How does the Osteosarcoma Information Hotline benefit your physician/oncology team?
Osteosarcoma is a rare cancer diagnosis, and often excellent and compassionate physician teams do not include an expert in this disease. Care teams in this situation routinely welcome the input offered by a disease expert like those that are available through the Osteosarcoma Information Hotline. These physicians are uniquely trained and experienced in the management of osteosarcoma, and their consultation may result in additional options or nuance in care to be considered by your physician team as it maintains continuity of direct clinical care.
Mother of Osteosarcoma Patient
The Osteosarcoma Hotline is an amazing resource for our family! As a mother with a 13 year old osteowarrior, I couldn’t rest without knowing I am doing absolutely everything to give her the best care. The Osteosarcoma Hotline gave me that peace of mind and the reassurance that I’m doing everything possible for my daughter. They are knowledgeable, kind and compassionate. I can’t thank the Osteosarcoma Institute enough for providing this service.
Gavin, osteosarcoma patient, connected to a
trial through the OSI Hotline
A Clinical Trial
The Osteosarcoma Institute is pleased to connect interested parties with CareBox, a free and confidential trial matching service that will help guide you through a search and referral process to find a clinical trial that may be right for you. This matching system shortens the clinical trial search process from weeks to minutes, helping users identify clinical trials with eligibility criteria that match a patient’s specific diagnosis, stage, symptoms, and treatment history. Fill out your contact information below, and a Clinical Trial Navigator will call you within one business day. Se Habla Español.
Here at The Osteosarcoma Institute, we care about progress, not credit. We believe the more people working on the problem, the better. We partner with like-minded organizations to co-fund osteosarcoma science and can establish a patient-family fund for families wishing to fund osteosarcoma studies and trials with the assistance of our organization.
Lizzy’s Walk of Faith Foundation
Lizzy’s Osteosarcoma Science Fund
In 2020, the Osteosarcoma Institute partnered with Lizzy’s Walk of Faith Foundation to establish Lizzy’s Osteosarcoma Science Fund. Together, we were able to raise $50,000 in honor of Lizzy, which will be applied to an osteosarcoma clinical trial or study in 2021. The founders of LWOF Foundation, Jennifer and John Wampler, will meet with OSI’s osteosarcoma experts to review proposals from our grant process. Together, with guidance from our profesionals, they will select which scientific effort to apply Lizzy’s Science Fund to.
#TeamIzzy’s Osteosarcoma Science Fund
In 2021, the Osteosarcoma Institute joined forces with osteosarcoma survivor, Izzy’s, family to start a fund in her name. Together, we have raised $100,000 in 2021, which will be applied to a breakthrough clinical trial or stufy in ostyeosarcoma this year. Of her experience opening a fund with OSI, Izzy says, “Research and trials are necessary to help kids like me. None of it can happen without money. The more we talk about it, the more people will know and the more they can help.
Rally Foundation & Osteosarcoma Institute
The Rally Foundation for Childhood Cancer Research partnered with the Osteosarcoma Institute to co-fund a Phase II Clinical Trial at MD Anderson Cancer Center. The Rally Foundation is dedicated to empowering volunteers to raise awareness and funds to find better treatments, and ultimately cures, for all pediatric cancers.
Emily, Osteosarcoma Survivor
Want to share your story with us?
Fill out the form below to tell us about yourself. Sharing stories of osteosarcoma families helps us raise awareness and funds for much-needed research.
Frequently Asked Questions
What is Osteosarcoma?
Osteosarcoma (OS) is the most common primary bone tumor seen in children/adolescents and young adults, with around 600 cases diagnosed yearly in the United States between the age of 10 and 30, and a peak incidence during the adolescent growth spurt. It can occur anywhere along with the skeleton, but the most common sites are in areas of extensive longitudinal bone growth, around the knee (distal femur and proximal tibia, and shoulder (proximal humerus). The overwhelming majority of OS cases requires both surgery and chemotherapy for curative treatment but about 1/3 of cases will relapse and metastasize. The most common site of metastatic disease in the lung, although metastases to bone also occur.
What are the symptoms of OS?
The most common presenting complaint of patients with OS is pain. The pain is commonly associated with some form of trauma, although there is no association of osteosarcoma with trauma. Since pain is so common among young active children and adolescents as is mild trauma, this presenting sign often is present for weeks to months prior to seeking medical attention, with the pain frequently becoming more persistent and often more severe over time, ultimately leading to medical attention. There may also be associated swelling over the area of pain that may also increase over time. Eventually, imaging of the affected area leads to the diagnosis.
What is a Clinical Trial?
What is Immunotherapy?
Introduction to Advancements in Cancer Treatments
What is Chemotherapy?
¿Qué es el Osteosarcoma?
El osteosarcoma (OS) es el tumor óseo primario más común observado en niños / adolescentes y adultos jóvenes, con alrededor de 600 casos diagnosticados anualmente en los Estados Unidos entre las edades de 10 y 30, y una incidencia máxima durante el período de crecimiento de la adolescencia. Puede ocurrir en cualquier lugar junto con el esqueleto, pero los sitios más comunes se encuentran en áreas de extenso crecimiento óseo longitudinal, alrededor de la rodilla (fémur distal y tibia proximal, y hombro (húmero proximal). La gran mayoría de los casos de SG requieren cirugía y quimioterapia para el tratamiento curativo, pero aproximadamente 1/3 de los casos recaerán y harán metástasis. El sitio más común de enfermedad metastásica en el pulmón, aunque también se producen metástasis en los huesos.
¿Cuáles son los síntomas del OS?
La queja de presentación más común de los pacientes con SG es el dolor. El dolor se asocia comúnmente con algún tipo de trauma, aunque no existe una asociación de osteosarcoma con trauma. Dado que el dolor es tan común entre los niños y adolescentes activos jóvenes como lo es el traumatismo leve, este signo de presentación a menudo está presente durante semanas o meses antes de buscar atención médica, y el dolor con frecuencia se vuelve más persistente y a menudo más severo con el tiempo, lo que finalmente conduce a problemas médicos. atención. También puede haber inflamación asociada sobre el área del dolor que también puede aumentar con el tiempo. Finalmente, la obtención de imágenes del área afectada conduce a la diagnóstico.
¿Qué son los Ensayos Clinicos?
¿Qué es la Inmunoterapia?
Fases de Prueba
¿Qué es la Quimioterapia?
from the Director’s Desk
Each month Osteosarcoma Institute Director, Dr. Lee Helman shares a reputable reading reccomendation to guide our supporters through learnings, breakthroughs, and updates in osteosarcoma and childhood cancer.
Targeting the VEGF Pathway in Osteosarcoma
June Reading Recommendation
In this review, we will discuss the pathophysiology, rationale, and role of targeting angiogenesis via the VEGF pathway in patients with osteosarcoma with emphasis on the published clinical trials and future directions. Citation: Assi,T.;Watson,S.;
Samra, B.; Rassy, E.; Le Cesne, A.; Italiano, A.; Mir, O. Targeting the VEGF Pathway
in Osteosarcoma. Cells 2021, 10, 1240. https://doi.org/10.3390/cells10051240
July Reading Recommendation TBA
August Reading Recommendation TBA