About Us

Concentrating On The Cure

Our Story

How the Osteosarcoma Institute Began

The OSI was initially conceived at an osteosarcoma expert panel conference held in Jackson Hole, Wyoming in the summer of 2015. That conference was convened by the WWWW Foundation (QuadW) as it approached its 10 year anniversary, seeking to assess the results of its historical funding of sarcoma research and looking for big ideas for the future.

Over the course of the conference, the evidence showed that there had been no progress in osteosarcoma treatments over the past ten years (in fact, over the past 35 years). A stark consensus emerged that the existing, traditional paradigm for seeking advancements had failed and a new paradigm was needed.

A Convening of Healthcare Visionaries

QuadW spent the next 18 months evaluating the impediments to progress and possible solutions. They conducted countless interviews and brainstorming sessions with sarcoma specialists, the broader cancer community, and healthcare visionaries. They examined successes in other cancers.

Willie, Osteosarcoma Patient and Inspiration of OSI with his mother, Lisa Tichenor

Cigall Kadoch, PhD, Strategic Advisory Board Member

A New Roadmap

The result of these efforts was a new roadmap that would:

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Establish a coherent osteosarcoma research and development agenda and develop the mechanisms to execute on that agenda

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Further elucidate the “omics” hallmarks and basic biology of osteosarcoma, and specifically its metastasis, with an eye toward translating discoveries into drugs that improve the survival of patients

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Increase the number of academic and commercial enterprises researching osteosarcoma

Our Goals

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Remove Obstacles

Remove obstacles to identifying a cure by pre-funding pre-clinical studies and revolutionary fast readout trials of unexplored aspects of osteosarcoma

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Fund Advancements

Fund clinical trials, translational grants, and osteosarcoma science to identify new treatment options for osteosarcoma patients for whom the first line of therapy has failed

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Accelerate Progress

Work together with the research, pharma, and clinical communities, monitor and develop the scientific landscape around OS to identify opportunities and accelerate progress

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Raise Awareness

Raise awareness and galvanize advocacy of osteosarcoma in communities across the United States

Dr. Lee Helman, OSI Director

Mission & Strategy

Our Strategy

Globally estimated, there are over 26,000 new cases of osteosarcoma diagnosed each year, with 900 being diagnosed in the US, but treatment options haven’t advanced in over 35 years. To find a cure for osteosarcoma, we have to collaborate, innovate, and translate around the most promising science.

Our Mission

The Osteosarcoma Institute’s mission is to dramatically increase treatment options and survival rates in osteosarcoma patients through identifying and funding the most promising and breakthrough osteosarcoma clinical trials and science.

Our Team

Leaders

Lee J. Helman, MD

Director

Chand Khanna, DVM, PhD

Strategic Advisory Board Chair

Strategic Advisory Board

Bret Alexander

Fernanda Arnaldez

Michael Brown, MD

Mary Katherine Clarke

Richard Gorlick, MD

Andrea Hayes-Jordan

Katherine Janeway, MD

Cigall Kadoch, PhD

Robert G. Mennel, MD

Melinda Merchant MD, PhD

Sung Poblete PhD, RN

Robert Schreiber, PhD

Alejandro Sweet-Cordero

Bill Tap, MD

Mac Tichenor

Daniel Von Hoff, MD, F.A.C.P.

Jinghui Zhang, PhD

Staff

Chelsey Blanks

Executive Assistant

Vivian Laws

Development Manager

OSI Board 

The OSI Board at their Inagural Meeting

Careers at The Osteosarcoma Institute

Current Job Openings

Scientific Project Manager for a virtual research institute

Scientific Project Manager for a virtual research institute

The OSI is seeking a Scientific Project Manager (SPM) to support and contribute to the activities of the OSI Strategic Advisory Board (SAB) and its scientific committees.
Osteosarcoma Institute, Development Manager

Osteosarcoma Institute, Development Manager

The Osteosarcoma Institute is seeking a full-time Fundraising Development Manager to help grow our organization in the fight to overcome osteosarcoma.
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